In such a harsh industrial environment, most of the companies are all looking for ways to reduce the cost and improve the quality. This research combine DEMATEL and Taguchi Method base on the D2MAIC model, and make it more objectively and systematically on critical parameters selecting. The effectiveness of critical parameters selecting model is verified in a case study of paper tube drying process, and the optimal factor-level combination is obtain by Taguchi Method. According to the result, the nonconforming rate decreased from 5% to 1.99%, the margin of improvement is 60.2%. The result has confirmed the feasibility.