白鶴靈芝葉部精油之含氧化合物成分分析

Studies on the Oxygenated Fraction of Essential oil Constituent from the Leaves of Rhinacanthus nasutus Lindau

紀景耀(CHIN-YAO CHI)

指導教授 ： 謝博進

中原大學/理學院/化學研究所/碩士(2012年)

https://doi.org/10.6840/cycu201200762

摘要

白鶴靈芝 (學名Rhinacanthus nasutus) 又名癬草，為爵床科植物，主要分佈於大陸的廣西、廣東、海南、雲南以及臺灣等東南亞地區。多為栽培，亦有野生於丘陵或荒地、路邊、河邊等濕潤環境地方。其味甘、微苦、性微寒、具有潤肺降火、殺蟲止癢等功效。早期用於肺結核、體癬、濕疹、皮膚搔癢等症。近年來臺灣之醫學專家發現用白鶴靈芝泡茶飲用對高血壓、糖尿病、動脈硬化、失眠、便秘以及婦女生理調節等有很好療效。
將新採的白鶴靈芝葉，經清洗、風乾之後，把葉子搗碎進行水蒸氣蒸餾，再經溶劑萃取(正己烷、乙醚)、鹼處理、水洗與濃縮等步驟，得其棕褐色的中性精油。中性精油經液相色層分析粗分，分成碳氫化合物和含氧基化合物兩大部分，並使用氣相層析-火焰離子偵測器(GC-FID)、氣相層析-質譜儀(GC-MS)、傅立葉轉換紅外光光譜儀(FT-IR)、核磁共振光譜儀(NMR)鑑定其化學成分。共鑑定出21個含氧化合物，其中單離出的成分有phytol 、6,10,14-trimethylpentadecan-2-one 、(E)-4-(2,6,6-trimethylcyclohexa- 1,3-dien-1-yl)but-3-en-2-one這3個化合物且純度有達到95%，而以GC-MS光譜儀鑑定出的成分有(Z)-hex-3-en-1-ol、benzaldehyde、2-phenylethanol、m-tolylmethanol、3,5,5-trimethylcyclohex-2-enone等18個化合物。

關鍵字

白鶴靈芝 ； 含氧化合物成分分析

並列摘要

Rhinacanthus nasutus, Acanthaceae plant, mainly in mainland China such as Guangxi, Guangdong, Hainan, Yunnan and Taiwan, Southeast Asia. Cultivation, also wild moist environment in the hills or wasteland, roadside, river place.
Its sweet and slightly bitter, slightly cold, lungs pathogenic fire, insecticidal antipruritic efficacy. Early for tuberculosis, tinea, eczema, skin pruritus embolism. In recent years, Taiwan's medical experts in Rhinacanthus nasutus tea drinking have a good effect on blood pressure, diabetes, arteriosclerosis, insomnia, constipation, and women's physiological regulation.
The leaves were freshly harvested from Rhinacanthus nasutus. After cleaning and immedately air-dried, the leaves were steam-distilled for essential oils. The essential oils in the distillate were then solvent extracted before treatment with base to remove acidic compounds. The slightly brown neutral essential oil mixture was separated and purified by column chromatography.
The oil mixture was chromatographed into hydrocarbon and oxygenated fractions that were analyzed for the chemical components by gas chromatography(GC) equipped with a flame ionization detector(FID) and mass spectrometer detector(MS), Fourier Transform infrared spectrometer(FT-IR), and nuclear magnetic resonance spectrometer(NMR). In the oxygenated fraction, (Z)-hex-3-en-1-ol, benzaldehyde, 2-phenylethanol,3,5,5-trimethylcyclohex-2-enone, m-tolylmethanol, 2,3-dihydrobenzofuran, 2,6,6-trimethylcyclohexa-1,3-dienecarbaldehyde, (Z)-2-phenylbut-2-enal, (E)-1-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)but-2-en-1-one, (E)-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-en-2-one, (E)-4-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)but-3-en-2-one, (E)-4-(buta-1,3-dien-1-yl)-3,5,5-trimethylcyclohex-2-enone, pentadecan-2-one, 6,10,14-trimethylpentadecan-2-one, methyl palmitate, isophytol, (9E,12E,15E)-octadeca-9,12,15-trien-1-ol, phytol, 2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione, 2-methylanthracene-9,10-dione, (2Z,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol were identified.

並列關鍵字

Oxygenated Fraction ； Rhinacanthus nasutus Lindau

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