以二氧化矽修飾磁性、螢光奈米顆粒製備之初步探討

Preliminary Study on Preparation of Magnetic and Fluorescent Nanoparticles Modified by Silica

林貞諭(Zhen Yu Lin)

指導教授 ： 傅傳博

國立暨南國際大學/科技學院/應用化學學系/碩士(2017年)

摘要

本篇論文之研究方向主要為利用多孔性二氧化矽(mSiO2)材料聚合在生物相容性低的硫化鋅硒化鎘 (CdSe/ZnS) 量子點以及氧化鐵之表面，並使其顆粒相較於本實驗室之前合成配方所合成出之量子點表面包覆多孔性奈米顆粒之外觀更接近球型；藉由將磁性及螢光奈米粒子表面修飾上二氧化矽，使兩種奈米顆粒可以進一步修飾上不同官能基，並且合成出具有磁性及螢光功能的功能性奈米顆粒。

關鍵字

多孔性二氧化矽 ； 量子點 ； 功能性奈米顆粒

並列摘要

This thesis focuses on preparations of using porous silicon dioxide modified iron oxide and cadmium selenide zinc sulfide (CdSe / ZnS) quantum dots. The motivation of this research is to make magnetic and fluorescent nanoparticles. The presence of porous silicon dioxide in the magnetic and fluorescent nanoparticles can make particles round sphere shape and also increase ability of attaching functional groups onto nanoparticles. Therefore we can easily create functional nanoparticles.

並列關鍵字

porous silicon dioxide ； quantum dots ； functional nanoparticles

參考文獻

1. Teo, B.M., et al., Sonochemical synthesis of magnetic Janus nanoparticles. Langmuir, 2011. 27(1): p. 30-3.

2. Popp, N., S. Kutuzov, and A. Böker, Various Aspects of the Interfacial Self-Assembly of Nanoparticles. Springer-Verlag Berlin Heidelberg, 2010. 228: p. 39-58.

3. El-Sadik, A.O., A. El-Ansary, and S.M. Sabry, Nanoparticle-labeled stem cells: a novel therapeutic vehicle. Clin Pharmacol, 2010. 2: p. 9-16.

4. Walther, A. and A.H. Muller, Janus particles: synthesis, self-assembly, physical properties, and applications. Chem Rev, 2013. 113(7): p. 5194-261.

5. Katherine E. Roelofs, T.P.B., Stacey F. Bent, Interface Engineering in Inorganic-Absorber Nanostructured Solar Cells. American Chemical Society, 2014. 5: p. 348-360.