高訊號雜訊比陣列式生物感測低功率讀出電路之研究

Research of High SNR Low Power Readout Circuit for Biosensor Array

褚鴻(Hung Chun)

指導教授 ： 孫台平

國立暨南國際大學/科技學院/電機工程學系/碩士(2014年)

摘要

本論文之研究方向是提高訊號雜訊比雙輸出陣列讀取電路架構，利用CTIA(Capacitve Transimpedance Amplifier)不需額外偏壓控制感測電流特色，適用於感應輸出較低之電流式生物感測器。在取樣訊號太低時，利用四對一加法原理使訊號雜訊比增加。由於偵測兩種生物感測器在復雜的心血管疾病做雙輸出相互關係比對，在功率消耗方面也是相當可觀的，另一方面現今生醫儀器強調可攜帶性，對功率消耗的問題是我們必須注意的，所以我們設計了低功率消耗讀出晶片。在整體的陣列感測電路架構上，加上低功率設計，使其功率消耗比原本的降低約55%，以達到了低功率消耗的目的。
該讀取電路採用TSMC 0.35um 2P4M 5V製程製作，單一像素布局面積為50μm×50μm，在這個面積內共有兩組電容式轉阻放大器型注入式的電路，分別連接兩種生物感測器，而且各自有16x12的陣列，故整體為32x12陣列讀出電路，其輸入電流範圍為100pA ~ 121nA，在取樣電壓足夠時訊號雜訊比為58dB，而利用加法開關增強訊號雜訊比為65 dB，在未有低功率的情形時功率消耗為14.15mw，而在啟用低功率的設計時其功率消耗為6.4mw。
本論文為了設計多種待測物偵測的優點以能配合各個疾病互相增長影響的關係做為陣列感測器生物讀出電路，可適用於大範圍亮度以及高均勻度影像讀取運用以及在使用在非侵入性偵測所感應出的極微小訊號和感測器在低樣品數目環境下輸出的微小電流，以自動影像系統來驗證晶片做切換模式以及均勻度的分析與探討。
關鍵詞：讀出電路、雙模輸出、螢幕顯像系統、訊號雜訊比、生醫陣列式讀出電路、低功率

關鍵字

影像顯示系統 ； 讀出電路 ； 雙波段感測 ； 訊號雜訊比 ； 生醫陣列式讀出電路 ； 低功率

並列摘要

In this paper, to improve the signal to noise ratio for dual model readout circuit. CTIA bias control with the stable voltage bias sensing, It applicable lower current sensing sensors. When the sampling voltage signals is too low we use a four by one signal summation to increase signal to noise ratio. Since the sensors detect two types of biological to compared double output relationship for complex cardiovascular disease so Power consumption is also considerable. On the other hand the biomedical instrumentation is emphasized portability now, so we must pay attention to power consumption. That's all we designed the lowpower readout chip. Its power consumption save about 55 percent which is lower than the original, to achieve purpose of the low-power readout circuits.
The circuit using TSMC 0.35um 2P4M 5V process production, the layout area of a single pixel is 50μm × 50μm, the single pixel have two CTIA circuit. Because single pixel connect the two biosensors so each of which has an array of 16x12, so the whole have array of 32x12. The readout circuit input current range of 100pA ~ 121nA, and signal to noise ratio is 58dB when summary switch no use, and the use of the summary switch to enhance signal to noise ratio obtain 65 dB. In the case of power consumption is about 14.15mw, in when you enable the design of low –power. Power consumption is 6.4mw.
In this research, has the advantage of variety of target can be detected. It can meet the two kind proportional relationship of cardiovascular disease as a multifunctional biosensor readout circuit. It suitable for a wide range of high brightness and uniformity of the image to read the use of an automated imaging system analysis and discussion of the chip verification do switch modes and uniformity.

Key word：ROIC, Dual-band Readout, Video display system, Signal to noise ratio, Biosesnor readout circuit, Low power

並列關鍵字

Video display system ； ROIC ； Dual-band Readout ； Signal to noise ratio ； Biosensor readout circuit ； Low power

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