下顎骨造釉細胞癌－病例報告

Ameloblastic Carcinoma of the Mandible: A Case Report

蔡樂霖(Lo-Lin Tsai) ； 曾志恩(Jeh-En Tzeng) ； 邱智弘(Chih-Hung Chiu)

《中華民國口腔顎面外科學會雜誌》 16卷2期 (2005/09) Pp. 128-142

https://doi.org/10.7104/CJOMS.200509.0128

摘要

造釉細胞癌為一罕見的顎骨齒源性腫瘤，好發於下顎骨後方區域，好發年齡平均為30.1歲，無性別上之差異。其主要的徵狀為顎骨及顏面的腫脹伴隨疼痛並有生長快速、牙關緊閉甚至焦慮不安等情形。在定義上惡性造釉細胞瘤與造釉細胞癌有所不同，前者用以描述具有遠端轉移情形但組織學上為典型的造釉細胞瘤，而後者為組織學上發生惡性轉變之造釉細胞瘤。造釉細胞癌的治療目前仍以手術切除為主，放射線治療及化學治療的療效尚未被證實。本文提出一例罹患下顎造釉細胞癌的患者，就其發病過程、臨床檢查、手術治療方式及追蹤情形作一完整之報告。

關鍵字

造釉細胞癌 ； 惡性造釉細胞瘤

並列摘要

Ameloblastic carcinoma is a rare odontogenic tumour of the jaws, the most commonly involved area is the posterior portion of the mandible, occurs in the mean age of 30.1 years and there is no apparent sex predilection. The most common sign described has been swelling, include associated pain, rapid growth, trismus and dysphonia. There are some different in the terminology of ”Malignant ameloblastoma” and ”Ameloblastic carcinoma”; ”Malignant ameloblastoma” refers to a neoplasm in which typical histologic features of ameloblastoma are seen in the primary tumour located in the jaw as well as in any associated metastatic deposits, and ”Ameloblastic carcinoma” described as ameloblastomas in which there had been histologic malignant transformation. The treatment of ameloblastic carcinoma has been recommended that surgical treatment with 2-3cm bony margins of jaw resection, the effects of radiotherapy and chemotherapy are as yet unproven. We reveal a case of ameloblastic carcinoma of the mandible and report present illness, clinical exam, surgical therapy treatment and post-operation follow up in particulars.

並列關鍵字

Ameloblastic carcinoma ； Malignant ameloblastoma