Intraosseous Schwannoma of the Mandible-A Case Report

下顎骨骨內許旺式細胞瘤－病例報告

張妤欣(Yu-Hsin Chang) ； 孫章唐(Jhang-Tang Sun) ； 黃冠閔(Kuan-Min Huang) ； 林立鵬(Li-Peng Lin) ； 蔡國陽(Kuo-Yang Tsai)

《臺灣口腔顎面外科學會雜誌》 24卷4期 (2013/12) Pp. 299-308

摘要

顎骨內許旺氏細胞瘤為罕見的疾病，源自神經髓鞘上的許旺氏細胞增生形成的良性腫瘤。許旺氏細胞瘤生長緩慢，一般發生在頭頸部的軟組織，尤其是口腔，而口腔內又以舌頭最多。文獻上統計，骨內腫瘤發生率約佔全身良性腫瘤的1%，尤其以下顎骨後緣和下顎骨枝發生率最高。最適當的處置為手術摘除及定期追蹤，復發及惡性變化機率極低。本文提出一位67歲男性病例，在右下顎骨體和下顎骨角的位置有一個多腔室的放射性透射病灶，同時有頰側骨頭膨脹，而病患明顯沒有疼痛或神經麻痺的情況。治療方法以手術摘除，並保留下齒槽神經，術後病人抱怨右下唇有輕微感覺異常，追蹤兩年後漸漸消失。

關鍵字

許旺氏細胞瘤 ； 神經髓鞘瘤 ； 骨內 ； 口腔

並列摘要

The intraosseous Schwannoma of the jaw is a rare case, which is a benign tumor. It is also called neurilemmoma and derives from nerve sheath (Schwarm cell). These slowly growing tumors most arise in the soft tissues of the head and neck. There are more frequent in the oral cavity. Tongue is the most common site. They are only 1% occurrence rate in the whole body bone tumor. Intraosseous Schwannoma occurs most in the posterior areas and ramus regions of mandible. The most proper treatment is conservative surgical excision with periodic follow-up. The recurrence and malignant change are extremely rare.We reported a 67-year-old male, with a large multilocular radiolucent lesion over right body and angle of mandible. Bony expansion over right buccal shelf was noted, without any pain or paresthesia. Surgical enucleation was performed and inferior alveolar nerve was protected intraoperatively. Only mild paresthesia over right lower lip was complained after operation, but the symptom/sign subsided after a 2-year follow-up.

並列關鍵字

Schwannoma ； Neurilemmoma ； Intraosseous ； Oral cavity