自體免疫性兩側突發性聽力障礙－病例報告

Autoimmune Inner Ear Disease Presenting as Bilateral Sudden Hearing Loss-Case Report

林太郎(Tai-Lang Lin) ； 詹光漢(Kuang-Han Chan) ； 許權振(Chuan-Jen Hsu)

《中華民國耳鼻喉科醫學雜誌》 34卷6期 (1999/11) Pp. 501-505

https://doi.org/10.6286/1999.34.6.501

摘要

自體免疫內耳疾病會出現兩側漸進式覺視經性聽力障礙，大多是在幾週或幾個月內形成，然而以突發性發生則少見。今經驗1例曾有體液免疫性檢查不正常的56歲女病人，主訴雙側突發性聽力障礙，體液免疫性的血清檢查發現：抗核酸抗體為1:5120(+)、類風濕性因子為 1:20480(+)，給予類固醇治療後聽力恢復，類風濕性因子降為 1:1028(+)，為一自體免疫內耳疾病。追蹤3年，未再復發。(中耳醫誌 1999;34:501-505)

關鍵字

自體免疫內耳疾病 ； 感覺視經性聽力障礙

並列摘要

The clinical picture of autoimmue inner ear disease consists of bilateral progressive sensorineural hearing loss. Although sensorineural hearing loss usually develops over weeks or months, sudden hearing loss may occur in some cases. A 56 year-old woman with autoimmune inner ear disease presented with sudden bilateral sensorineural hearing loss, dizziness and tinnitus. An auditory brainstem response test revealed bilateral cochlear lesions. The anti-nuclear antibody test was positive at a titer of 1 : 5120, and the rheumatoid factor test was positive at a titer of 1: 20480. Autoimmune inner ear disease was diagnosed from patient’s clinical manifestations, positive immune laboratory tests, and beneficial treatment response to prednisolone 1 mg/kg/day for one week. This patient was discharged one week after admission and no recurrence or complications were noted on OPD follow-up after 3 years.

並列關鍵字

autoimmune inner ear disease ； sensorineural hearing loss