運用掃描電子顯微鏡直接觀察尿液沉積物分析尿路結石成份

Direct Observation of Urinary Sediment by Scanning Electron Microscopy to Analyze Urinary Stone Composition

楊國強(Kuo-Chung Yang) ； 李瀛輝(Ying-Heui Lee) ； 陳明村(Ming-Tsun Chen) ； 黃榮慶(Jong-Khing Huang) ； 張心湜(Luke S. Chang)

《中華民國泌尿科醫學會雜誌》 2卷4期 (1991/12) Pp. 608-612

https://doi.org/10.7024/JUAROC.199112.0608

摘要

體外電震波碎石後常因結石碎片收集不易致使結石診斷率無法提昇。為了克服這個問題，我們收集了26位病人在碎石術前後不同時間的尿液標本並在掃描電子顯微鏡下觀察以比較其結石出現率及診斷率。結果我們發現無論結石出現率或診斷率均以在碎石後隔日清晨的第一次小便為最高，分別是76%及50%。如果合併觀察碎石後的第一次小便及隔日早晨的第一次小便的話，其結石診斷率更可高達70%。掃描電子顯微鏡的應用加上正確地選擇收集尿液標本的時間，可以明顯地提昇體外電震波碎石術後病人的結石診斷率。

關鍵字

掃描電子顯微鏡 ； 體外電震波碎石術 ； 結告分析

並列摘要

In urolithiasis patients treated with extracorporeal shock wave lithotripsy (ESWL), because of the passed stone fragments were often minute and urine specimmen collection was frequently troublesome, so the rate of stone analysis are relatively low. In order to overcome this embarrassing condition, a prospective study was performed to evaluate the efficacy of scanning electron microscopy (SEM) on urine sediment to analyze urianry stone composition. Three timed urine specimens were collected, i.e., the urine in the morning befroe ESWL. We also compared the stone composition analyzed simutaneously by SEM and infrared spectrophotometer in 10 patients. Our results showed that both stone occurrence rate and diagnosis rate were highest in the ruine specimen available from the next morning after WSWL, which were 76% and 50%, respectively. Furthermore, the stone diagnosis rate could be even higher (70%) if we combined the findings of urine specimen immediately after ESWL. In conclusion, direct observation of urine sediment by scanning electron microscopy to analyze stone is an easy, cconvenient and accurate method, patient usually can get stone analysis result befor discharge from hospital.

並列關鍵字

scanning electron microscope ； extracorporeal shock wave lithotripsy ； stone analysis