- 期刊
喉部惡性纖維性組織細胞瘤－病例報告
Malignant Fibrous Histiocytoma of the Larynx - Case Report
摘要
惡性纖維性組織細胞瘤通常發生在上下肢的皮膚、肌肉、肌鍵和關節，比較少發生於頭頸部、發生於喉部者更是罕見。一般認為惡性纖維性組織細胞瘤來自組織細胞或原始基質細胞，顯微鏡下可見腫瘤細胞呈現特殊的漩渦狀排列。喉部的惡性纖維性組織細胞瘤容易復發，且會轉移至身體其他器官，但頸部轉移則較少見。治療以手術切除為主，並可輔以化學治療，而放射線治療通常效果不佳。成大醫院耳鼻喉科於民國81年7月經歷一男性病例，予以施行全喉摘除術治療，術後復原良好，追蹤迄今無復發或轉移現象。
並列摘要
Malignant fibrous histiocytoma usually occurs in the soft tissues, tendons and joints of the upper and lower extremities. It is uncommon in the head and neck region and rare in the larynx. Malignant fibroblastic and hisiocytic cells ofter arranged in a storiform pattern. In the larynx, this tumor displays an aggressive biologic behavior, it may recur and metas-tasize to various organs. The treatment of choice is wide resection. We experienced a 59-year-old male patient with the complaints of hoarseness for 4 months and dyspnea for 1 month. He received total laryngectomy in July 1992. The pathology revealed malignant fibrous histiocytoma. Post-operative course was uneventful. There is no evidence of recurrence or distant metastasis so far.
延伸閱讀
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