Pharyngoesophageal perforation caused by oral endotracheal intubation is an unusual case clinically. A 77-year-old male patient suffered from hemoptysis, mild fever, sore throat and neck swelling after receiving sclera buckling and vitrectomy under general anesthesia. In group consultation with otolaryngologists, the physical examination revealed local tenderness over bilateral neck and crepitus over left neck. Computer assisted tomography scan showed emphysema in the posteior pharyngeal and bilateral lateral pharyngeal space. So it was suspected that the patient had a pharyngeal perforation after receiving oral endotracheal intubation. Although incision, debridement and primary closure of a perforated wound at the left lateral pharyngeal wall were performed, the wound healing was poor. Therefore, the wound was reopened and kept on wet dressing on a long term basis until it healed up. The patient was followed up and stable for half a year since completion of the operation.