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摘要


原發於鼻咽的腺癌是非常罕見的,嚊咽腺癌大約佔所有鼻咽惡性腫瘤的2-5%。分化不良的鼻咽腺癌對放射線治療的效果極差,且容易轉移預後差。本篇報告-罕見分化不良的鼻咽腺癌合併頸部轉移的病例,雖然接受較積極之放射線治療併化學治療,仍然發生肺部轉移,於發病後19月死亡。病理組織切片以EBER原位雜合法顯示嚊咽及轉移頸部的腺癌腫瘤細胞中,大部份含有EBER1於細胞核內。

關鍵字

鼻咽腺癌 分化不良

並列摘要


Primary adenocarcinoma of the nasopharynx is a rare tumor. Only 2-5% of all nasopharyngeal cancers are adenocarcinoma. Nasopharyngeal poorly differentiated adeno-carcinoma is beliveved to be resistant to radiation, easy metastasis and poor prognosis. In this report we present a 58 year-old man with a primary nasopharyngeal poorly differentiated adenocarcinoma and neck metastasis. The primary tumor and neck masses achieved a complete response after a concurrent chemoradiotherapy. Unfortunately, bilateral lung metastases were noted 6 months after the completion of treatment. The patient died in spite of aggressive chemotherapy.

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