石蓮(Graptopetalum Paraguayens）之水與甲醇萃取液之抗氧化性與對Streptozotocin(STZ)誘發糖尿病大鼠血糖的影響

Effect of Shi-lan (Graptopetalum Paraguayens) Extracts on Antioxidative Performance and Serum Glucose Level in Streptozotocin-induced Diabetic Rats

楊景雍(Jiang-Iong Yang) ； 潘敏雄(Ming-Hsiung Pan) ； 蔡美玲(Mei-Ling Tsai) ； 陳文傑(Wen-Chieh Chen)

《高雄海院學報》 18期 (2003/12) Pp. 119-132

摘要

本研究將探討以動物模式驗證石蓮（Graptopetalum Paraguayens）葉體之萃取物對誘發性糖尿病大鼠之血糖是否有改善功效，並以石蓮葉體的水與甲醇萃取液，評量其抗氧化性。結果顯示兩者中，甲醇萃取液有較強抗氧化性，而在為期五週實驗內，顯示連續灌食石蓮葉體水與甲醇萃取物，可逐漸改善誘發性糖尿病大鼠體內血糖的調控，使血糖值逐漸降低，並在葡萄糖耐性試驗，2小時內調降血糖值。

關鍵字

石蓮葉體 ； 糖尿病 ； 抗氧化性 ； 血糖值

並列摘要

The objective of present work is to identify the functionality of Shi-lan (Graptopetalum Paraguayens) with an in vivo study. A Streptozotocin-induced diabetic animal model is employed to investigate the effect of Graptopetalum Paraguayens for reduction of blood glucose level. By using of water and methanol extraction from Sh-ilan, the antioxidative activities and its effect on blood glucose level in diabetic rats are examined. Data obtained shows that the extract from methanol exhibits a higher antioxidative activity than that from water, and blood glucose level can be reduced by both of two extracts.

並列關鍵字

Graptopetalum ； Paraguayens leaf ； diabetics ； antioxidative activity ； blood glucose level