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Ecthyma Gangrenosum and Palate Necrosis in a Healthy Cleft Patient

顎裂患者綠膿桿菌感染併上顎及咽壁壞死-病例報告及文獻回顧

摘要


敗血症合併壞死性皮膚炎造成相當高死亡率,綠膿桿菌是較常見的菌種。在較少的清況下麴菌屬,大腸桿菌,及某些黴菌也會引起類似疾病。壞死性皮膚炎臨床上的變化很多樣性,從小丘疹到廣泛的組織壞死都可能發生,較可能發生的部位是四肢、腋下,及腹股溝、上顎壞死的案例則很少被報告。我們從文獻回顧找到四例報告,所有這些病人均發生綠膿桿菌感染後發生廣泛性上顎及咽壁壞死的案例重建及長期追蹤的結果並就文獻做回顧。

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並列摘要


Ecthyma gangrenosum is a severe form of tissue infection most commonly by pseudomonas aeruginosa. Usually it is associated with sepsis and high mortality rate. It occurs on patients with defective defense mechanism. The skin lesions typically involve axillary, gluteal, groin areas, and extremities. Palatal and pharyngeal wall involvement has been rare. We present a case with cleft lip and palate who was otherwise healthy. He developed sepsis and ecthyma gangrenosum with extensive involvement and tissue necrosis on palato-pharyngeal area. The infection was successfully controlled and the palatal defect was satisfactorily reconstructed.

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