Measurement of Portal and Splenic Blood Flow by Pulsed Doppler Ultrasound in Normal Subjects and Patients with HBsAg-Positive Chronic Liver Disease

利用都卜勒超音波測量正常人及HBsAg陽性之肝疾患者門，脾靜脈之血流量

林漢傑(Han-Chieh Lin) ； 蔡養德(Yang-Te Tsai) ； 李壽東(Shou-Dong Lee) ； 張定宗(Ting-Tsung Chang) ； 李發耀(Fa-Yauh Lee) ； 王聖賢(Sung-Sang Wang) ； 黃以信(Yi-Shin Huang) ； 賴啓賢(Chii-Shyan Lay) ； 羅光瑞(Kwang-Juei Lo)

《中華民國消化系醫學會雜誌》 5卷4期 (1988/12) Pp. 193-200

https://doi.org/10.6557/GJTa.198812_5(4).0002

摘要

Pulsed Doppler ultasound was performed in 23 normal subjects, 10 patients with chronic hepatitis B and 18 patients with hepatitis B surface antigen positive liver cirrhosis. Portal venous velocity was significantly reduced in patients with chronic hepatitis (16.8±2.7cm/sec, p＜0.05) and cirrhosis (14.1±2.6cm/sec, p＜0.00l) compared to normal subjects (21.4±5.0cm/sec). The cross sectional area of portal vein was significantly increased in cirrhotic patients (1.19±0.36cm^2) compared to normal subjects (0.65±0.19cm^2, p＜0.001) and patients with chronic hepatitis (0.75±0.13cm^2, p＜0.00l). In addition, the cross sectional area of splenic vein was also significantly increasedin cirrhotic patients (0.82±0.29cm^2) compared to normal subjects (0.35±0.16cm^2, p＜0.001) and patients with chronic hepatitis (0.32±0.09cm^2, p＜0.001). No significant difference in portal blood flow were found among different group of subjects. However, a fairly good correlation (r=0.81, p＜0.001) was found between portal blood flow and cross sectional area of the portal vein in cirrhotic patients. In addition, the splenic blood flow increased significantly in cirrhotic patients (11.2±3.9ml/mm/kg) compared to patients with chronic hepatitis (5.0±1.2ml/mm/kg, p＜0.0l) and normal subjects (5.2±1.9ml/mm/kg, p＜0.0l). There was no relationship between portal blood flow and size of esophageal varices. The pulsed Doppler ultrasound provide a nonivasive evaluation of the portal hemodynamics in patients with chronic liver disease.

關鍵字

門靜脈血流 ； 都卜勒超音波 ； 慢性肝病

並列摘要

Pulsed Doppler ultasound was performed in 23 normal subjects, 10 patients with chronic hepatitis B and 18 patients with hepatitis B surface antigen positive liver cirrhosis. Portal venous velocity was significantly reduced in patients with chronic hepatitis (16.8±2.7cm/sec, p＜0.05) and cirrhosis (14.1±2.6cm/sec, p＜0.00l) compared to normal subjects (21.4±5.0cm/sec). The cross sectional area of portal vein was significantly increased in cirrhotic patients (1.19±0.36cm^2) compared to normal subjects (0.65±0.19cm^2, p＜0.001) and patients with chronic hepatitis (0.75±0.13cm^2, p＜0.00l). In addition, the cross sectional area of splenic vein was also significantly increasedin cirrhotic patients (0.82±0.29cm^2) compared to normal subjects (0.35±0.16cm^2, p＜0.001) and patients with chronic hepatitis (0.32±0.09cm^2, p＜0.001). No significant difference in portal blood flow were found among different group of subjects. However, a fairly good correlation (r=0.81, p＜0.001) was found between portal blood flow and cross sectional area of the portal vein in cirrhotic patients. In addition, the splenic blood flow increased significantly in cirrhotic patients (11.2±3.9ml/mm/kg) compared to patients with chronic hepatitis (5.0±1.2ml/mm/kg, p＜0.0l) and normal subjects (5.2±1.9ml/mm/kg, p＜0.0l). There was no relationship between portal blood flow and size of esophageal varices. The pulsed Doppler ultrasound provide a nonivasive evaluation of the portal hemodynamics in patients with chronic liver disease.

並列關鍵字

splenoportal blood flow ； pulsed Doppler ultrasound ； chronic liver disease