顎骨漿細胞肉芽腫－病例報告

漿細胞肉芽腫為一罕見的反應性增生病灶，好發於肺，少見於口腔，其中充滿了以多株性漿細胞為主的急、慢性發炎細胞浸潤。由於臨床特徵及放射線學檢查表現易於與惡性腫瘤混淆，通常需要組織病理檢查，配合免疫組織化學染色來確定診斷。漿細胞肉芽腫的治療以手術切除為主，對於無法以手術切除的病灶，考慮使用高劑量類固醇藥物及放射線作為輔助治療。本病例於左側下顎骨無牙嵴處舌側有一4×2×2公分隆起之腫塊，電腦斷層顯示一囊狀的放射透性病灶，伴隨下顎骨皮質骨因腫瘤擴張而變薄。病灶可以完整的切除，可見邊緣清楚但無被膜，並可見到頰舌但及咬合面皮質骨板穿孔，下齒榜神經露出，病理報告為漿細胞肉芽腫。術後追蹤，傷口癒合良好，無神經受損等併發症。目前追蹤2年，並沒有腫瘤復發之跡象。

關鍵字

漿細胞肉芽腫；炎性假性腫瘤；顎骨

並列摘要

Plasma cell granuloma is a rare reactive proliferous lesion, composed of mainly polyclonal plasma cells accompany with acute and chronic inflammatory cells infiltrated. It manifests primarily in the lungs, but rare in the oral cavity. Because of the clinical features and radiological expression of the plasma cell granuloma are easily misdiagnosed with malignant tumor, it needs pathological examination combined with immunochemical stain to confirm the diagnosis. The first choice of treatment of the plasma cell granuloma is surgical excision. Adjunctive high dose steroid or radiotherapy reserved for the lesion which can not be surgical excised In this case, a protruding mass revealed on the edentulous ridge of the left mandible about 4 x 2 x 2 cm in size. After CT examination, it presents a budding expansile radiolucency lesion with ventral cortical bone wall off. After the tumor was excised, the pathological report confirmed it as a plasma cell granuloma. The patient has been followed for 2 years, and no sign of recurrence is found.

並列關鍵字

plasma cell granuloma ； inflammatory pseudotumor ； jaw bone

國際替代計量

顎骨漿細胞肉芽腫－病例報告

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