口腔鱗狀細胞癌合併發生肝細胞癌－病例報告

依臺灣地區十大死亡原因統計資料，自民國七十一年以來，癌症即躍居首位。其中肝癌對男性而言，是所有癌症死因的第一位；而對於女性，它也高居第二位。每年造成約四千人死亡，對國人健康造成極大威脅。此外，口腔癌在台灣之盛行率與致死率也與日俱增，成為台灣十大癌症之第六名，在男性則為第四名。在民國九十四年即造成死亡人數1513人，大約每六小時即有一人死於口腔癌。檳榔除已知與口腔癌、食道癌、咽癌有關外，最新研究也認為可能與肝癌、肝硬化、糖尿病等疾病的發生有關。本報告提出一例口腔癌合併同時發現肝癌之病例，並回顧肝細胞癌與口腔鱗狀細胞上皮癌之病理發生相關性、治療方式、遠端轉移率及治療預後因素。因病例之特殊故提出討論。

關鍵字

口腔鱗狀細胞癌；肝細胞癌

並列摘要

Due to the alteration of the dietary and the progression of medication, the main cause of death in Taiwan has been changed from acute infectious disease to chronic disease. The main cause of death was cancer since 1982 in Taiwan. Hepatocellular carcinoma is the second most common tumor in Taiwan, and causes an estimated 5750 cases and 7415 deaths in the year of 2008. At the same time, the prevalence and lethality of oral cancer in Taiwan has increased. It has become the sixth most common cancer, and caused 1513 people death. It is well know that alcohol consuming, cigarette smoking and betel quid chewing is major risk factors of oral cancer. Recently, It was mentioned that those may also play a role in pathogenesis of liver cancer. In Taiwanese population, people with the habit of betel chewing are more than 10%. About 86% of those ones were smokers and 75% were alcohol drinkers. We present a case of oral squamous cell carcinoma concomitantly with hepatocellular carcinoma. The relationship between HCC and SCC is also discussed, including the etiology, treatment, and prognosis, by a case of liver cancer and oral cancer combined.

並列關鍵字

oral squamous cell carcinoma ； HCC

國際替代計量

口腔鱗狀細胞癌合併發生肝細胞癌－病例報告

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