Cemento-ossifying Fibroma of Maxilla-A Case Report and Literature Review

上顎牙骨質骨化纖維瘤－病例報告及文獻回顧

成函潔(Han-Chieh Cheng) ； 雷文天(Man-Tien Lui) ； 高壽延(Shou-Yen Kao) ； 楊政杰(Cheng-Chieh Yang)

《臺灣口腔顎面外科學會雜誌》 27卷4期 (2016/12) Pp. 311-317

摘要

牙骨質骨化纖維瘤爲頭頸部之良性腫瘤。本篇報告討論一位18歲女性病患因左側上顎腫脹而求診，詳細理學檢查後發現爲一無症狀之腫脹硬塊於左側上顎處。經局部麻醉手術切除病灶後，病理報告證實爲罕見之上顎牙骨質骨化纖維瘤。術後一年追蹤並無復發病灶。文獻回顧指出牙骨質骨化纖維瘤是牙齒周圍牙周韌帶中的幹細胞衍生而來，顯微鏡下可發現富含纖維細胞組織、板層骨、編織骨及無細胞組織沉積物。本篇文章内容將本病例與過去文獻中病例之臨床特徵及組織病理學之差異做一比較。牙骨質骨化纖維瘤爲良性腫瘤但少數病例可能復發，提出此病例及文獻回顧以供研究及治療之參考。

關鍵字

牙骨質骨化纖維瘤 ； 骨化纖維瘤

並列摘要

Cemento-ossifying fibroma is a benign neoplasm that arising from jaw bones. Here, we report a rare case of cemento-ossifying fibroma occurred at maxilla in a 18 year-old female who presented an asymptomatic bulging out mass at left maxilla. She underwent enucleation with curettage of the lesion under local anesthesia and there were no complications upon 2 weeks follow- up and no recurrence noted 1 year post-operatively. In reviewing articles, cemento-ossifying fibroma arise from the stem cells of periodontal ligament surrounding teeth. It is a well-demarcated lesion composed of fibrocellular tissue, lamellar bone, woven bone and acellular deposition. The clinical features, histopathological findings of this disease will be reviewed and the differences of the current case were compared. In general, it is a benign neoplasm but may recur in some cases.

並列關鍵字

Cemento-ossifying fibroma ； Ossifying fibroma