口底單發性纖維瘤－病例報告及文獻回顧

Solitary Fibrous Tumor of Floor of Mouth-A Case Report and Review of the Literatures

黃峻德(Chun-De Huang) ； 葉麗青(Khin Than Win) ； 林哲毅(Che-Yi Lin)

《臺灣口腔顎面外科學會雜誌》 32卷4期 (2021/12) Pp. 264-273

摘要

單發性纖維瘤是一種罕見的頭頸部軟組織腫瘤。單發性纖維瘤最早是由Klemperer及Rabin西元1931年首次發表於文獻中的肋膜腔腫瘤。於頭頸部區域內，鼻腔、鼻竇及眼球區域是目前發生比例較高的區域，其次為口腔區域及唾液腺。單發性纖維瘤在口腔內較常出現於頰黏膜及舌，初期症狀多為無痛及緩慢生長之實質腫瘤。女性好發率有些微偏高。本文提出之病例，為一名41歲女性於左側口底發現一個3公分無痛且橡膠質地腫瘤長達3至4年，經過臨床相關檢查及全身麻醉下進行腫瘤切除及左側舌下腺摘除術，最終病理報告顯示為單發性纖維瘤。術後九個月後進行核磁共振檢查並無腫瘤復發及殘留之狀況。文中針對單發性纖維瘤相關診斷及治療追蹤等進行文獻回顧及討論。

關鍵字

單發性纖維瘤 ； 口底

並列摘要

Solitary fibrous tumor (SFTs) is a rare neoplasm of the head and neck region. SFT was first described in the pleura in 1931 by Klemperer and Rabin. The sinonasal tract and orbit were the most common sites involved in head and neck regions, followed by the oral cavity and salivary glands. SFT in oral cavity often occurs in buccal mucosa and tongue, most commonly present as a painless and slow-growing mass. There was a slight female predilection. In our case, a 41-year-old female found a painless mass of left side floor of mouth with rubbery consistency in the past 3-4 years. After clinical and radiographic examination, she received the surgery of total sublingual gland lobectomy under general anesthesia. The final pathological diagnosis was SFT. After 9 months follow up, no local recurrence was shown. We also reviewed related articles and discussed the differential diagnosis and treatments of SFTs.

並列關鍵字

Solitary fibrous tumor ； Floor of mouth