Pathologic tooth migration is a common finding associated with periodontal disease. When it occurs in the anterior region is called diastema. Diastema always changes the appearance and is the common reason for them to go to the dentist. The patient, a 25-year-old female went to our OPD for diastema on her upper anterior teeth. After oral examination, we found the diastema between #11, #21 was caused by chronic periodontitis. She received periodontal therapy including initial therapy and flap surgery on the maxillary anterior teeth and the right posterior teeth; guided tissue regeneration was done with Biomend membrane combined DFDBA between #11, #21 and occlusal adjustment. During supportive periodontal treatment, about four months after active periodontal therapy, spontaneous correction of pathologic tooth migration was noticed and stayed stable till now.