非糖尿病成年男性抽菸習慣與軀體脂肪分佈的相關性研究

中心性軀體脂肪分佈與人類的健康問題有關，為了探討抽菸習慣與軀體脂肪分佈的相關性，我們收集1993-1994年間至成大醫院住院健康檢查病房受檢之非糖連病健康成年男性共253人為研究對象。分析資料包括腰臀圍的比值、身體質量指數、年齡、教育程度、婚姻狀態、抽菸及喝酒習慣、運動習慣及職業狀態等。依據抽菸習慣獎研究對象區分為從未抽菸、已戒菸、輕中度抽菸以及重度抽菸四組分析其腰臀圍比值發現，重度抽菸者比從未抽菸者或輕中度抽菸者均有較高的腰臀圍比值，而且腰臀圍比值有隨著抽菸量的增加而上升的趨勢；亡戒菸者的腰臀圍比值雖略高於從未抽菸以及輕中度抽菸者，但皆未達到有意義的差異。以複迴歸線性分析發現年齡、身體質量指數及抽菸習慣均為影響腰臀圍比值的獨立因子。本研究發抽菸習有促使軀體脂肪趨向腹部中心性分佈的傾向。同時，隨著每日抽菸量的增加，其腰臀圍的比值也隨之增加，顯示了抽菸對於軀體脂肪分佈的影響有劑殘效應(dose dependent effect)存在的可能。

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並列摘要

There is a close correlation between the centrality of body fat distribution and human health. To assess the relationship between smoking habit and body fat distribution, a total of 253 healthy non-diabetic male admitted to NCKUH for a 2-day hospitalized health physical check up from 1993 to 1994 were enrolled. After an overnight fasting, biochemistry examination was arranged and waist-to-hip ratio (WHR) was measured for each subject. Personal socio-behavioral factors including educational status, marital status, smoking and drinking habit, exercise habit and occupational status were obtained by structured questionnaires. To compare the dose-dependent response, the subjects were classified into four subgroups: never smoker, ex-smoker, mild to moderate smoker and heavy smoker. The results showed that heavy smokers had significantly higher WHR than non-smokers or mild to moderate smokers. A positive trend between WHR and daily smoking consumption was also found. Ex-smokers had a higher, though not statistically significant, WHR than never-smokers or mild to moderate smokers. The age, body mass index and smoking habit were independent variables to WHR, using the multiple linear regression analysis. In conclusion, our results indicate that smoking habit has a dose related influence on the body fat distribution, favoring abdominal accumulation in non-diabetic male Chinese.

並列關鍵字

waist-to-hip ratio ； smoking ； body fat distribution ； dose-dependent effect

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非糖尿病成年男性抽菸習慣與軀體脂肪分佈的相關性研究

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