神經母細胞瘤18例之臨床分析報告

Clinical Study of 18 Cases of Neuroblastoma

林清輝(Chin-Huei Lin)

《Acta Paediatrica Sinica》 6卷2期 (1965/06) Pp. 76-81

摘要

神經母細胞瘤是發生在嬰孩與孩童期最多的惡性瘤之一。Dargeon報告1926年到1961年1833個發生在嬰孩與孩童期癌症病人中神經母細胞瘤有205例(11%)。不僅因它的死亡率極高，而且因其隱成襲的發生與複雜的臨床過程，常使醫師在診斷上及治療上感到很大的困惑。有些神經母細胞瘤的病例易於診斷，但有很多不僅使醫師煞費頭腦，甚至有時富有經驗的病理專家亦迷惑不解。著者就1954年至1963年的10年間在台大醫院小兒科住院的神經母細胞瘤病例爲材料，報告並檢討其臨床經過、診斷、治療及預後等。

並列摘要

The author reported 18 cases of pathologically confirmed neuroblastoma admitted to the Pediatric Ward of National Tai wan University Hospital during the recent 10 years from 1954 to 1963. in this series the youngest was 16 days old, the oldest 12 years and 5 months old, and the average age 3 years and 5 months. 83.4% of the cases were under the age of 5 years. The longest survival time was 13 months, while the average survival time was 5.3 months in the 7 followed up cases. Two interesting cases; one with unusual symptoms and course was treated with B18, Endoxan, Erythrophyll and X-ray irradiation and survived 13 months, the other one whose abdominal tumor was surgically removed and still living 20 months after the operation, are reported. A brief analysis of the symptoms, laboratory and roentgenological findings, and treatment is presented.