飲食蛋白量對大白鼠酒精嗜好性的影響

Effect of Dietary Protein Level on Alcohol Preference in Rats

江孟燦(Meng-Tsan Chiang) ； 盧明傑(Min-Jer Lu)

《中華民國營養學會雜誌》 21卷3期 (1996/08) Pp. 263-277

https://doi.org/10.6691/JCNS.199608_21(3).0004

摘要

To clarify the relationship between alcohol taste preference and nutritional status, the effect of dietary protein level on the preference for alcohol solution was studied in male SD (Sprague Dawley) rats for 8 weeks. Casein was used as protein source, and the animals were divided into two groups, 5% protein group and 15% protein group. Deionized water and alcohol solution containing 5% ethanol (v/v) were prepared in water suppling graduated tubes and the animals were allowed free choice of these solution. Body weight, plasma triglyceride and plasma total protein levels were higher observed in rats fed 15% protein diet than those fed 5% protein diet. In addition, significantly increased liver ADH (alcohol dehydrogenase) and ALDH (acetaldehyde dehydrogenase) activities were found in the 15% dietary protein group. However, rats fed 5% protein diet had high cumulative alcohol solution intake and low cumulative water intake. In addition, significantly increased plasma GOT (glutamate oxaloacetate transaminase) activity was observed in rats fed 5% protein diet. Results from the present study suggest that dietary protein may play an important role in alcohol preference in rats.

關鍵字

酒精嗜好性 ； 飲食蛋白質 ； 大白鼠

並列摘要

To clarify the relationship between alcohol taste preference and nutritional status, the effect of dietary protein level on the preference for alcohol solution was studied in male SD (Sprague Dawley) rats for 8 weeks. Casein was used as protein source, and the animals were divided into two groups, 5% protein group and 15% protein group. Deionized water and alcohol solution containing 5% ethanol (v/v) were prepared in water suppling graduated tubes and the animals were allowed free choice of these solution. Body weight, plasma triglyceride and plasma total protein levels were higher observed in rats fed 15% protein diet than those fed 5% protein diet. In addition, significantly increased liver ADH (alcohol dehydrogenase) and ALDH (acetaldehyde dehydrogenase) activities were found in the 15% dietary protein group. However, rats fed 5% protein diet had high cumulative alcohol solution intake and low cumulative water intake. In addition, significantly increased plasma GOT (glutamate oxaloacetate transaminase) activity was observed in rats fed 5% protein diet. Results from the present study suggest that dietary protein may play an important role in alcohol preference in rats.

並列關鍵字

alcohol preference ； dietary protein ； rats