眼瞼皮脂腺癌－30例之研究報告

目的：眼瞼皮脂腺癌是華人常見的眼瞼惡性腫瘤，本文乃探討眼瞼皮脂腺癌之臨床特性。病人與方法：本文自民國69年至89年間，於台大醫院及亞東醫院，共收集30例眼瞼皮脂腺癌，皆有病理切片證實。結果：平均追蹤48.4 ± 54.5個月（3至113個月），女性多於男性，平均為68.1 ± 9.3歲，發生於上眼瞼為最多（56.7%），病灶多小於1公分，治療方法以手術切除為主，術前正確診斷率達62.9%，自治療後至復發或轉移期間平均為17.5 ± 13.4個月，以統計學分析（Kaplan-Meier survival analysis），五年之復發率為26.0%，五年因腫瘤之死亡率為12.1%。結論：治療此症宜採手術切除配合冷凍切片檢查，以確定腫瘤完全清除。

關鍵字

皮脂腺癌；眼瞼；死亡率；復發率

並列摘要

Objective: Sebaceous carcinoma of the eyelids is relatively common among eyelid cancers in Chinese. The purpose of this study is to investigate the clinical characteristics of sebaceous carcinoma of the eyelids. Patients and Methods: Between 1980 and 2000, 30 patients with histopathologically confirmed eyelid sebaceous carcinoma were collected at National Taiwan University Hospital and Far Eastern Memorial Hospital in Taiwan. Results: A follow up study was undertaken for 28 patients. The mean follow up period was 48.4 ± 54.5 months (range 3-113 months). There were 21 women and 9 men. The mean age at diagnosis was 68.1 ± 9.3 years. Tumors developed most commonly on the upper eyelid (56.7%). The size of most lesions was found within 1 cm. The most common treatment modality was surgical excision. The rate of accurate diagnosis was 62.9%. The mean interval to recurrence or metastasis was 17.5 ± 13.4 months. A 5-year recurrence rate of 26.0% was noted on Kaplan-Meier survival analysis. The 5-year tumor-related mortality rate was 12.1%. Conclusion: Surgical excision with frozen section is important to ensure complete removal of the tumor.

並列關鍵字

sebaceous carcinoma ； eyelid ； mortality rate ； recurrence rate

國際替代計量

眼瞼皮脂腺癌－30例之研究報告

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