- 期刊
過敏性鼻炎患者皮膚試驗與ImmunoCAP檢查之相關性
The Correlation between Skin Test and ImmunoCAP Test in Patients with Allergic Rhinitis
摘要
BACKGROUND: We investigated the correlation between skin test and ImmunoCAP test in patients with allergic rhinitis by comparing results obtained. METHODS: From June 2001 to November 2002, 71 patients with allergic rhinitis received intradermal skin tests which included 5 common inhalant allergens and Pharmacia CAP tests which included 8 common inhalant allergens within 24 hours. The results of skin tests were considered positive if the diameter of the skin erythema was larger or equal to 10 mm and the results of PharmaciaCAP tests were considered positive if the specific IgE titer was more than 0.35 u/ml. The results of skin tests and PharmaciaCAP tests for the same 5 inhalant allergens (house dust, common ragweed, dog dander, Aspergillus and Candida) were compared. RESULTS: For house dust, common ragweed, dog dander, Aspergillus and Candida, the positive rates of skin tests were 81.7%, 39.4%, 39.5%, 7% and 50.7%, and the positive rates of PharmaciaCAP tests were 74.6%, 16.9%, 18.4%, 0% and 2.8%. Using McNemar's test analysis, no significant differences were found between the results of skin tests and PharmaciaCAP tests for house dust (p＞0.05), but there were significant differences between the results of skin tests and PharmaciaCAP tests for common ragweed, dog dander and Candida (p＜0.05). Comparison of the results of skin tests and PharmaciaCAP tests for Aspergillus using McNemar's test analysis could not be performed because the positive rate for PharmaciaCAP tests for Aspergillus was 0%. CONCLUSIONS: In this study, the positive rates of skin tests were higher than those of PharmaciaCAP tests for the same 5 inhalant allergens (house dust, common ragweed, dog dander, Aspergillus and Candida). The differences were significant between the results of skin tests and PharmaciaCAP tests for common ragweed, dog dander and Candida but were not significant for house dust.
並列摘要
BACKGROUND: We investigated the correlation between skin test and ImmunoCAP test in patients with allergic rhinitis by comparing results obtained. METHODS: From June 2001 to November 2002, 71 patients with allergic rhinitis received intradermal skin tests which included 5 common inhalant allergens and Pharmacia CAP tests which included 8 common inhalant allergens within 24 hours. The results of skin tests were considered positive if the diameter of the skin erythema was larger or equal to 10 mm and the results of PharmaciaCAP tests were considered positive if the specific IgE titer was more than 0.35 u/ml. The results of skin tests and PharmaciaCAP tests for the same 5 inhalant allergens (house dust, common ragweed, dog dander, Aspergillus and Candida) were compared. RESULTS: For house dust, common ragweed, dog dander, Aspergillus and Candida, the positive rates of skin tests were 81.7%, 39.4%, 39.5%, 7% and 50.7%, and the positive rates of PharmaciaCAP tests were 74.6%, 16.9%, 18.4%, 0% and 2.8%. Using McNemar's test analysis, no significant differences were found between the results of skin tests and PharmaciaCAP tests for house dust (p＞0.05), but there were significant differences between the results of skin tests and PharmaciaCAP tests for common ragweed, dog dander and Candida (p＜0.05). Comparison of the results of skin tests and PharmaciaCAP tests for Aspergillus using McNemar's test analysis could not be performed because the positive rate for PharmaciaCAP tests for Aspergillus was 0%. CONCLUSIONS: In this study, the positive rates of skin tests were higher than those of PharmaciaCAP tests for the same 5 inhalant allergens (house dust, common ragweed, dog dander, Aspergillus and Candida). The differences were significant between the results of skin tests and PharmaciaCAP tests for common ragweed, dog dander and Candida but were not significant for house dust.
延伸閱讀
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