In the current time of inclusion education, the general education teachers are facing more and more problems and challenge for students with special education need. In order to salve the problems, many specialists think general education teachers can through the way to collaborate with special educators and other professionals, as well as to use co-teaching to satisfied students' special needs. In this essay, I will discuss the collaboration and co-teaching between special educators and general education teachers from several topics base on the inclusion education: the meaning and salient of co-teaching, the collaboration and the way to co-teaching between teachers, and the practice of co-teaching.