新型親水性表面處理鈦金屬人工牙根臨床人體試驗之研究探討

A new SLAffinity titanium dental implant clinical trial research and discussion

陳冠仲(Guan-Jung Chen)

指導教授 ： 黃茂栓

臺北醫學大學/口腔醫學院/牙醫學系碩博士班/碩士(2015年)

https://doi.org/10.6831/TMU.2015.00084

摘要

本案例分享為使用國內第一家通過衛署認證之國產人工牙根系統Ti-one®
101(HC-Bios dental implant system)，並揭露出創新之親水性表面處理技術
SLAffinity，SLAffinity表面處理因表面具有微米、次微米及奈米級複合型孔洞的氧
化鈦層，且具有極佳的親血性質，致使提高初期植體穩固度及骨癒合的效果；於
動物實驗將其與SLA 表面處理的植體系統比較顯示：不管在植入三周、六周、九
周後，移除扭力均大於SLA 表面處理，證實SLAffinity具有加速骨癒合之效果，
故本研究將以臺灣植體製造廠鴻君科技之Ti-one® 101(HC-Bios dental implant
system)進行人體臨床試驗（TMU-JIRB No. 201111017），探討創新表面處理技術之
Ti-one® 101 植體的骨癒合及成功率

關鍵字

親水性表面處理

並列摘要

For the use of the first domestically certified implant system Ti-one® 101
(HC-Bios dental implant system) by the Department of Health, to reveal the
innovative hydrophilic-surface treatment technology SLAffinity . SLAffinity surface
treatment has the excellent hemotrophic property due to micron, sub-micron and
nanoscale composite holes covering on the titanium oxide layer, resulting in
improved stability of the implant body and the effect of osseointegration. In animal
experiments, comparing Ti-one® 101 with the surface treated with SLA system shows:
whether three weeks, six weeks, nine weeks later, Ti-one® 101 has more removal
torque than just SLA surface treatment, confirming that SLAffinity can accelerate
bone healing and osseointegration. So our study will use Ti-one® 101 (HC-Bios dental
implant system) in human clinical trials (TMU-JIRB No. 201111017), to explore this
innovative surface treatment technology and the success rate of osseointegration.

並列關鍵字

SLAffinity

參考文獻

microscopical analysis of laser-treated titanium implant surfaces*a comparative

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treatments of titanium dental implants for rapid osseointegration, Dental Materials.

Cooper, Review Advancing dental implant surface technology - from micron to

nanotopography, Biomaterials. 29 (2008) 3822-3835.