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Testing the Acceptability of Liquid Fish Oil in Older Adults

測試老年人對液態魚油的接受度

摘要


炎症性疾病受益于鱼油治疗的可能性常见于老年人,可是老年人對魚油的接受性并不确定。这研究旨在评估,對老年人,不同浓度的液態鱼油之适口性、鱼油副作用的频率和程度、和总结鱼油治疗的所有效應。研究分两部分,共計100位患者(≥60岁),完成一项随机单盲的适口性試驗。第一部分,50位受試者,以随机抽样次序,攝取多次液体鱼油樣品(2x10%,40%和100%)。在第二部分,50位受試者分別品尝其中一个鱼油样本,或100%的淡味橄榄油(对照组)。受試者对油样本味道的喜好度,以5点計分的Likert量表來评估。对于油样本之副作用,在品尝后24小时被记录。第一部分的结果表明,9/50受試者报告,随着鱼油的浓度增高,令人不悅的味道亦上昇。有14/50的受試者不喜歡100%鱼油的口味,有7/50的受試者覺得10%鱼油不適口。14/50受試者报告有鱼油的副作用,但这不会影响他们對治疗的依从性。至于第二部分,1/12品尝100%鱼油与0/13品尝10%鱼油或橄榄油的受試者,宣稱有不悅的味道。4/50受試者报告有副作用,而其中2位表示这会阻止他们繼續进行鱼油治疗。结论是,味道本身并不会妨礙鱼油治疗。此外,报告的副作用有可能不是对于鱼油的真正反应,或阻止患者遵从治疗。液体鱼油补充剂老年人可接受,因此針對治疗老年状况应加以调查。

關鍵字

魚油 老年人 接受度 品嘗 副作用

並列摘要


Inflammatory conditions likely to benefit from fish oil therapy are prevalent in older adults however acceptability in this group is uncertain. This study aimed to assess the palatability of a range of liquid fish oil concentrations, the frequency and extent of side effects, and to summarise any effects on adherence to fish oil therapy in older adults. One hundred patients (≥60 years) completed a randomised, single-blind palatability study, conducted in two parts. In part one, 50 subjects, blinded to random sample order, consumed multiple liquid fish oil samples (2x10%, 40% and 100%). In part two, 50 subjects tasted one concentration, or 100% extra light olive oil (control). Pleasantness of taste was scored on a 5-point Likert scale. Side effects were recorded 24-hr post-tasting. Results of part one showed that 9/50 participants reported increasingly unpleasant taste with increasing fish oil concentration. 14/50 reported unpleasant taste for 100% fish oil vs 7/50 for 10%. 14/50 reported side effects which would not affect compliance with therapy. For part two, 1/12 reported unpleasant taste for 100% vs 0/13 for 10% fish oil or control. 4/50 reported side effects and 2/4 indicated these would prevent ongoing fish oil therapy. The authors conclude that taste itself is not a deterrent to fish oil therapy. Furthermore, reported adverse effects may not be a true reaction to fish oil, or dissuade patients from compliance. Liquid fish oil supplements are acceptable to older adults, therefore should be investigated as a therapy for geriatric conditions.

並列關鍵字

fish oils older adults acceptability taste adverse effects

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