人工關節磨損表面相對機械性質研究

為了評估可能導致人工髖關節鬆脫原因中，有關磨耗殘屑造成骨溶解的問題、及相對機械性質造成材質磨損的程度。本研究以模擬磨耗機試著趨近髖關節之動態生物力學方式，並取其最大步態值；加速負荷磨損表面的磨耗變化，以收集磨耗屑；評估殘屑釋出的速率、形態、做定性及定量分析。以掃描式電子顯微鏡、感應耦合電漿質譜儀、電子能譜化學分析儀分別在30萬、60萬、100萬及130萬測試次對濾片或循環液做磨耗殘屑分析，結果顯示：殘屑形態會隨測試次，依序形成小泡狀聚集，而後呈較巨觀的片狀結構；殘屑成份包括：金屬氧化物、聚乙烯殘屑及可能由兩者所形成之化合物等。磨耗殘屑的增量與測試次呈同一趨勢，但因片狀物質產生，隨測試次增加而使增率呈上升關係。此結果有助於臨床觀察上，對骨溶解以致於人工關節鬆脫原因之瞭解。

關鍵字

超高分子聚乙烯；磨耗殘屑；形態；應變硬化

並列摘要

This study approaches to predict factors leading to loosening effect of hip joint prosthesis. In particular, wear-associated debris provokes bone tissue osteolysis and relative diversity in mechanical properties at the articulating surfaces caused different degree of wear. This study assumed an accelerated condition for a simulation, tried to interpret the occurrence of wear debris generation and collected wear species. Furthermore, the wear species were characterized by estimating the released sequences, morphologies and doing qualitative and quantitative analyses. Scanning Electron Microscope, Inductively Coupled Plasma Mass Spectrometer and Electron Spectroscopy for Chemical Analysis were used for the filtered samples or circulated liquid, at 300K, 600K, 1.0 M and 1.3 M testing cycles, respectively. Current studies have shown that morphologies and concentrations of wear debris varied with testing cycles, which generated in sequence: initial agglomerates, e.g. carbonates from scissioned polyethylene in spherical foam, and then delaminated plate-like structures. The composition might include: metallic oxides, carbonates and mixed compounds. Accumulation of released mass increased with testing cycles, but it showed an upward relationship, probably due to delaminating at polymer surface. This simulation may provide practical data as a reference for comparing with clinical observations, further osteolysis studies, as well as loosening evolution occurred at the articulating surfaces.

並列關鍵字

UHMW polyethylene ； wear debris ； morphology ； strain-hardening

國際替代計量

人工關節磨損表面相對機械性質研究

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