Title

梔子化學成分之HPLC分析

Translated Titles

Studies on Chemical Components of Gardeniae Fructus by HPLC

DOI

10.6945/ARFDR.201112.0383

Authors

謝詠筌(Yung-Chuan Hsieh);呂康祖(Kang-Tsu Lu);溫彩玉(Tsai-Yu Wen);劉宜祝(Yi-Chu Liu);羅吉方(Chi-Fang Lo)

Key Words

梔子 ; 鑑別 ; geniposide ; HPLC ; Gardeniae Fructus ; Gardenia jasminoides Eills ; geniposide ; HPLC

PublicationName

食品藥物研究年報

Volume or Term/Year and Month of Publication

2期(2011 / 12 / 08)

Page #

381 - 387

Content Language

繁體中文

Chinese Abstract

梔子(Gardeniae Fructus)為常用中藥之一,《神農本草經》列為中品,中華中藥典規範其基原為茜草科(Rubiaceae)植物梔子Gardenia jasminoides Eills的乾燥成熟果實。常誤用藥材為水梔子Gardenia jasminoides Eills var. granidiflora Nakai,雖為梔子之變種植物,但其外觀性狀、組織與成分含量仍有一定差異,應予區別。有鑑於此,本研究為了解市售梔子藥材之使用情形,搜集梔子對照藥材,由外觀性狀特徵及薄層層析法加以確認基原,再利用高效液相層析法,針對其指標成分geniposide進行定量。結果發現市售21件檢體均為梔子正品,其geniposide含量為4.12-7.13%,符合中華中藥典規範geniposide含量不得低於2%之規範,而建立之高效液相層析方法,可不受其他成分干擾,對3種梔子之指標成分有良好的分離效果。

English Abstract

The botanical origin of Gardeniae Fructus is fruit of Gardenia jasminoides Eills. According to literatures, G. jasminoides var. grandiflora is an alternative. Twenty-one samples were purchased from market and were distinguished from authentic material by morphology, and thin layer chromatographic analysis. In addition, the amount of geniposide was determined by high-performance liquid chromatography. The results showed that all samples were G. jasminoides. The amounts of geniposide in those samples ranged from 4.12 to 7.13%. According to Chinese pharmacopoeia Gardeniae Fructus shall contain not less than 2% of geniposide, as the result, all samples were qualified for the specification. Three marker compounds, geniposide, gardenoside and geniposidic acid of Gardeniae Fructus could also be separated by this HPLC method.

Topic Category 醫藥衛生 > 藥理醫學
Times Cited
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  2. 董珈瑄(2017)。益生菌與中藥草組合對仔豬生長及改善下痢之效果評估。中興大學動物科學系所學位論文。2017。1-96。