This paper presents the findings of a study which examined the relationship between transformational leadership, trust, commitment, and employee performance. Further, the study determined the influence of transformational leadership, trust, and commitment on employee performance. Although these interrelations are very important for enhancing performance, few empirical studies analyze these relationships together. Finally, the study examined the most important factor that influences employee performance. This article explores those relationships using SEM with data from 452 employees and their immediate supervisors of manufacturing firms located in Vietnam. The results indicated that transformational leadership indirectly enhances employee performance through employee trust and organizational commitment. Besides, employee trust influences employee performance, both directly and indirectly through organizational commitment. On the other hand, there is a positive association exists between organizational commitment and employee performance. Findings, implications and recommendation for future research from this study are discussed.