Basal Cell Carcinoma with Delayed Lung Metastasis: A Case Report

基底細胞癌合併延遲性肺轉移

張益嘉(Yi-Gia Chang) ； 盧崇正(Chong-Chen Lu) ； 彭瑞鵬(Reury-Peng Perng)

《胸腔醫學》 22卷6期 (2007/12) Pp. 399-404

https://doi.org/10.29806/TM.200712.0004

摘要

基底細胞癌為台灣最常見的皮膚惡性腫瘤。最近幾年以來，隨著全世界普遍紫外線暴露大量增加的緣故，使其發生率如其他皮膚腫瘤一樣的逐漸增加。原發性基底細胞癌通常可以很容易地切除乾淨，且預後極為良好。發生遠處轉移是相當罕見的，且於西元1894年至西元2004年十二月間國際間僅有268個個案被發表出來。我們在此發表一個肛門旁基底細胞癌做過根除性外科切除術，卻於手術十九年後發生肺部遠處轉移的個案。病患的胸部X光片和胸部電腦斷層均顯示兩側肺部散佈著瀰漫性、多發性的開洞式結節。後來由經電腦斷層導引肺部穿刺切片得以確定診斷。藉由這個個案我們希望能用以提醒臨床醫師，雖然基底細胞癌與其他皮膚惡性腫瘤比起來有較為良性之表現，但其依舊有延遲性復發或發生遠處轉移的可能性。

關鍵字

皮膚癌 ； 基底細胞癌 ； 轉移性基底細胞癌

並列摘要

Basal cell carcinoma is the most common skin cancer in Taiwan. The incidence is increasing because of the much higher exposure to ultraviolet radiation worldwide in recent years. Primary basal cell carcinoma can usually be well-excised and the prognosis is typically favorable. Distant metastasis occasionally occurs; only about 268 cases have been reported between 1894 and September 2004. We report a case of basal cell carcinoma of the perianal area and the status post-complete surgical excision with lung metastasis 19 years later. Chest radiography and chest computed tomography (CT) showed diffuse multiple cavitary nodules of the bilateral lung fields. The diagnosis was confirmed via CT-guided biopsy. Although basal cell carcinoma is relatively benign compared with other skin cancers, the possibility of delayed recurrence or distant metastasis should be considered.

並列關鍵字

skin cancer ； basal cell carcinoma ； metastatic basal cell carcinoma