實驗性近視之研究Ⅷ網膜特定區域對近視眼球生長發育之控制

遮蔽性近視被認為是和局部網膜因子的控制有關，但到底是那一個地區控制著近視的生成呢？我們以三個月大台灣彌猴作研究，對右眼作光凝固術，左眼則不作當做對照眼。第一隻是對黃斑部作雷射光凝固術，第二雙則對週邊視網膜（除黃斑部外）作光凝固術，第三隻則對視神經盤作雷射光凝固術。另外四隻同年齡彌猴則未作留下當做對照組。每年追蹤其屈光度及眼軸長之變化。三年後，我們發覺黃斑部雷射眼產生-2.0D的近視，而其對側眼則是-1.13D。週邊網膜雷射眼則為+0.63D和對照組+0.88D相近，其對側眼也產生了-0.63D的近視。至於視神經雷射眼則偏向遠視+2.75D，其對側眼也產生+3.0D之遠視。由以上結果，我們認為以雷射破壞週邊視網膜似乎可抑制近視之產生，反之破壞黃斑部則反而產生近視。所以我們認為網膜確實對眼球之發育生長之控制具重要角色。至於黃斑部如何控制近視之產生有持進一步探討。

關鍵字

無資料

並列摘要

Purpose. Visual deprivation myopia was suggested to be controlled by the local retina factor. We ought to explore which part of the retina, either macula or peripheral retina or optic nerve, is the critical area for visual deprivation myopia. Methods. Three 3-month-old baby moneys were studied. Laser photocoagulation was applied to the posterior pole of the retina on right eye, the left eye leaves without treatment. The first monkey was treated on macular area (MA) and the second one was treated on optic nerve (ON), the third one was treated on whole retina except macular area (PRP). Another 4 monkeys leave for controls in which they did not receive any laser treatment. The refractive stauts and ocular dimensions were measured on each year. Results. After 3 years, the mean refractive error of 4 control monkeys was +0.88D. The MA monkey showed myopia -2.0D on the right experimental eye and myopia -1.13D on the left control eye. The ON monkey showed moderate hyperopia on both eyes, +2.75D on the experimental eye and +3.0D on the control fellow eye. The PRP monkey showed slight hyperopia +0.63D on the right experimental eye and -0.63D on the left control eye. Conclusions. These results suggested that deprivation of the whole retina except macula inhibit ocular growth and produce similar refractive status as the control group. In contrast, deprivation of macular area during the age of visual development may produce slight myopia in monkey. Thus, retina may play some role in the development of myopia, but further study is necessary to clarify the role of macula in the development of refractive status in monkeys.

並列關鍵字

Experimental myopia ； Local retinal factors ； Macula ； Peripheral retina ； Photocoagulation

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實驗性近視之研究Ⅷ網膜特定區域對近視眼球生長發育之控制

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