Vanessa Fuchs-Tarlovsky;Karolina Alvarez-Altamirano;Deborah Turquie-Sacal;Carolina Alvarez-Flores;Hellen Hernandez-Steller

卵巢癌患者接受腫瘤治療前的營養狀態及體組成變化

Vanessa Fuchs-Tarlovsky ； Karolina Alvarez-Altamirano ； Deborah Turquie-Sacal ； Carolina Alvarez-Flores ； Hellen Hernandez-Steller

《Asia Pacific Journal of Clinical Nutrition》 22卷3期 (2013/08) Pp. 426-430

https://doi.org/10.6133/apjcn.2013.22.3.12

摘要

Poor nutritional status is a common problem among ovarian cancer patients. In order to detect changes in nutritional status and body composition this study investigates anthropometrical and biochemical parameters among these patients. This study included women with ovarian cancer and woman without cancer. Body composition was assessed by bioelectrical impedance analysis (BIA), anthropometrically, and with DXA scan, and total serum protein, albumin, transferrin, hemoglobin, hematocrit levels and total lymphocyte count was also measured. Data from DXA scan and body composition as assessed by BIA was collected from thirty-one women. Student t-test was used to compare differences in means between groups. This study included 120 women, 57 with ovarian cancer and 63 with benign tumors. Both groups of women were overweight. Body fat by skin-fold thickness, arm circumference, serum albumin, total lymphocytes count, as well as transferrin levels were significantly lower in the ovarian cancer group (p＜0.05). Ovarian cancer women had lower fat reserves by skin-fold thickness and lower serum proteins even though they were overweight. However, further studies need to use a body composition assessment on all subjects to confirm these results.

關鍵字

卵巢癌 ； 營養狀態 ； 體組成 ； 營養評估 ； 生物電阻抗分析

並列摘要

Poor nutritional status is a common problem among ovarian cancer patients. In order to detect changes in nutritional status and body composition this study investigates anthropometrical and biochemical parameters among these patients. This study included women with ovarian cancer and woman without cancer. Body composition was assessed by bioelectrical impedance analysis (BIA), anthropometrically, and with DXA scan, and total serum protein, albumin, transferrin, hemoglobin, hematocrit levels and total lymphocyte count was also measured. Data from DXA scan and body composition as assessed by BIA was collected from thirty-one women. Student t-test was used to compare differences in means between groups. This study included 120 women, 57 with ovarian cancer and 63 with benign tumors. Both groups of women were overweight. Body fat by skin-fold thickness, arm circumference, serum albumin, total lymphocytes count, as well as transferrin levels were significantly lower in the ovarian cancer group (p＜0.05). Ovarian cancer women had lower fat reserves by skin-fold thickness and lower serum proteins even though they were overweight. However, further studies need to use a body composition assessment on all subjects to confirm these results.

並列關鍵字

ovarian Cancer ； nutritional status ； body composition ； nutritional assessment ； bioelectrical impedance analysis

參考文獻

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Goft BA, Mandel LS, Drescher CW, Urban N, Gough S, Schurman KM et al. Development of an ovarian cancer symptom index: Possibilities for earlier detection. Cancer. 2007;109:221-7. doi: 10.1002/cncr.22371

Vine MF, Calingaert B, Berchuck A, Schildkraut JM. Characterization of prediagnostic symptoms among primary epithelial ovarian cancer cases and controls (Abstract). Gyn Oncol. 2003;90:75-82. doi: 10.1016/S0090-8258(03)00175- 6

Shike M. Nutrition therapy for the cancer patients. Hematol Oncol Clin North Am. 1996;10:221-34. doi: 10.1016/S0889 -8588(05)70336-1

Gil KM, Frasure HE, Hopkins MP, Jenison EL, Von VE. Body weight and composition changes in ovarian cancer patients during adjuvant chemotherapy. Gyn Oncol. 2006;103: 247-52. doi: 10.1016/j.ygyno.2006.03.005