Treatment Results of Carcinoma of the Nasal Cavity

鼻癌之治療結果

許智捷(Chih-Chiech Hsu) ； 鍾娜娜(Na-Na Chung) ； 雷德(Louis-Tak Lui) ； 丁禮莉(Lai-Lei Ting)

《放射治療與腫瘤學》 6卷3期 (1999/09) Pp. 197-202

https://doi.org/10.6316/TRO/199906(3)197

摘要

目的：評估鼻癌之治療結果。
材料和方法：從1977至1991，40位經病理切片證實鼻癌之病人在本院接受確定之開刀、放射治療、及術後放射治療，根據佛羅裏達大學分期方法計算其存活率，死因存活率，局部控制率和頸部控制率。
結果：從第一至三期之五年局部控制率分別為76%,84%,55%。五年存活率及死因存活率分別為54%及64%。從第一至三之五年存活率為88%,60%,38%。合併手術及放射治療，僅作放射治療和僅作手術之五年存活率為63%,45%,75%。
結論：期別、頸部淋巴轉移為主要之預後因數。治療方式、年齡、性別、病理型態、源起部位對預後並無顯著影響。預防性頸部放射治療對預防頸部復發可能無明顯益處。

關鍵字

鼻癌 ； 術後放射治療 ； 放射治療 ； 手術

並列摘要

Purpose: To evaluate the treatment results of carcinoma of the nasal cavity in one single institution.
Materials and Methods Forty patients with pathologically-proved carcinoma of nasal cavity received definite treatment such as surgery alone (4 cases, 10%), radiotherapy alone (22 cases, 55%), or post-operative radiotherapy (14 cases, 35%). Staging system of the Florida University was used in this study. Absolute survival, cause-specific survival, local control, and regional neck control were calculated.
Results The 5-year local control rates for stage Ⅰ through stage Ⅲ were 76%, 84% and 55%, respectively. The overall 5-year and cause-specific survival were 54% and 64%, respectively. Overall five-year survival for stage Ⅰ through Ⅲ were 88%, 60% and 30%, respectively. Five-year survival of different treatment methods by operation and postoperative radiotherapy, radiotherapy alone, and operation alone revealed 63%, 45% and 75%, respectively.
Conclusion: Initial stage and neck nodal status were significant prognostic factors. Treatment methods, age, gender, histology, and sites of tumor origin were not significant factors. Elective neck irradiation might have no significant benefit for the prevention of neck failure.

並列關鍵字

Carcinoma of the nasal cavity ； Post-operative radiotherapy ； Radiotherapy ； Surgery