Fish Induced Anaphylactic Reaction: Report of One Case

魚引起的過敏性反應：一病例報告

林鴻瀛(Horng-Ying Lin) ； 徐世達(Shyh-Dar Shyur) ； 傳仁良(Jen-Liang Fu) ； 賴永清(Yung-Ching Lai) ； 林振實(Jenn-Shyr Lin)

《Acta Paediatrica Sinica》 39卷3期 (1998/06) Pp. 200-202

https://doi.org/10.7097/APS.199806.0200

摘要

我 們報告一個四歲大男童，在最近二年，只要一接觸魚製品，即引發過敏性反應。臨床症狀包括喉嚨、眼睛癢，全身荨麻疹和臉部血管性水腫。這些症狀常伴隨咳嗽、喘鳴及呼吸困難。幾乎所有的魚製品，均會引發這些反應，包含不同種類的魚（鱈魚、鮪魚、鮭魚、鱒魚、鏝魚……），魚湯，魚罐頭，甚至筷子接觸魚製品後再食用，也會引起過敏反應。
實驗室檢查發現，病童體內免疫球蛋白E總量有明顯增加(224IU/ml)，而且對鱈魚、鮪魚、鮭魚、鱒魚、鰻魚、鯖魚的特殊免疫球蛋白E，均有明顯增加之情形。對魚的皮膚穿刺試驗出現正反應。使用鱈魚、鮪魚、鮭魚、鱒魚及鰻魚來作食物激發試驗，也出現過敏反應。病童的過敏反應經過嚴格的避免魚食物及藥物治療後，獲得很好的控制。另外值得一提的是，病童同時也會對青蛙有類似的過敏反應。
魚引起的過敏反應，最好的治療方式是避免接觸魚製品。嚴格的避免魚製品，可能需包括魚製品之食用及烹調時蒸氣的吸入。

關鍵字

魚 ； 過敏性反應

並列摘要

In the past 2 years, a 4 year-old boy has had an anaphylactic reaction whenever he contacted food prepared with fish. The symptoms included intense itching in the throat and eyes, which progressed to generalized urticaria and facial angioedema. This was accompanied by cough, wheezing and dyspnea. Many fish preparations caused these episodes including several different kinds of fish (cod, tuna, salmon, trout, eel...), fish soup, chopsticks contaminated with fish preparations and canned fish. Elevated levels of total serum IgE (224 lU/ml) and specific IgE for cod (93.1 lU/ml), tuna (＞100 lU/ml), salmon (＞100 lU/ml), trout (64.4 lU/ml), mackerel (41.2 lU/ml) and eel (28.1 IU/ ml) were found by the Pharmacia CAP system RAST FEJA in our allergy clinic. A skin prick test for mixed fish extracts (contain flounder, cod and halibut) was positive. A fish challenge test for cod, tuna, salmon, trout and eel all showed anaphylactic reactions. His allergic symptoms stabilized gradually after strictly avoiding ingestion of fish and using drug treatment. He also had a similar anaphylactic reaction to frogs. The best treatment for fish allergy is avoidance. Avoidance of fish may need to include both ingestion and inhalation of cooking vapors.

並列關鍵字

fish ； anaphylaxis