金門縣金城鎮第二型糖尿病患者視網膜病變盛行率及相關因素

Prevalence and Associated Factors of Diabetic Retinopathy among Type 2 Diabetic Subjects in Kin-Chen, Kinmen

周碧瑟(Pesus Chou) ； 曹雪琳(Hsueh-Lin Tsao) ； 董道興(Tao-Hsin Tung) ； 曾國亮(Gou-Liang Zeng) ； 陳水湖(Swei-Hu Chen)

《中華公共衛生雜誌》 19卷2期 (2000/04) Pp. 109-118

https://doi.org/10.6288/CJPH2000-19-02-05

摘要

目標；探討金城鎮糖尿病患者視網膜病變之盛行率與相關因子。方法：本研究以陽明十字軍於1992至1994年於金城鎮針對30歲以上居民篩選出的糖尿病患360人為研究對象，於1996及1997年由同一位眼科專科醫師以間接眼底鏡進行散瞳眼底檢查來論斷視網膜病變，總共完成237人。完成率65.8%。結果：研究結果發現237名糖尿病患者中，36位有視網膜病變，盛行率為15.2% , 其中背景期糖尿病視網病變7.2%、前增殖期糖尿病視網膜病變7.2%、增殖期糖尿病視網膜病變0.8%。多變項對數迴歸分析結果發現，糖尿病患病期間每增加一年期視網膜病變盛行率增加1.3倍(95%信賴區間為1.2-1.4)，糖化血色素每增加1%其盛行率增加1.3倍(95%信賴區間為1.1-1.5)，微量白蛋白尿≧50 mg/1者的盛行率是微量白蛋白尿＜50 mg/1的3.7倍(95%信賴區間為1.3-10.6)。女性的盛行率是男性的3.8倍(95%信賴區間為1.4-10.1)。結論：本研究發現糖尿病患視網膜病變盛行率為15.2%，糖尿病患病期間長、糖化血色素高、微量白蛋白尿高、以及性別（女性高於男性）均為影響糖尿病視網膜病度的相關因子。

關鍵字

第二型糖尿病 ； 視網膜病變 ； 盛行率 ； 相關因子

並列摘要

Objectives: To study the prevalence and associated factors of retinopathy among type 2 diabetics in Kin-Chen. Methods: A cross-sectional study on retinopathy among 360 diabetic subjects, screened by the Yang-Ming Crusade from inhabitants aged 30 and over in Kin-Chen in 1992-1994, was carried out in 1996-1997 by an ophthalmologist using indirect ophyhalmoscopy to examine the fundus after dilating pupils for the diagnosis of diabetic retinopathy. In total, 237 (65.8%) subjects were examined. Results: Thirty-six of 237 diabetics were diagnosed with diabetic retinopathy. The prevalence was 15.2%, including background diabetic retinopathy 7.2%, pre-proliferative diabetic retinopathy 7.2, and proliferative diabetic retinopathy 0.8%. Based on multiple logistic regression analysis, the significant associated factors for diabetic retinopathy were duration of diabetes (OR=1.3, 95% CI: 1.2-1.4), HbA1c (OR=1.3, 95% CI: 1.1-1.5), microalbumin (≧50 mg/1 vs. ＜50 mg/1, OR=3.7, 95% CI: 1.3-10.6), and sex (female vs. male, OR=3.8, 95% CI: 1.4-10.1). Conclusions: This study found that the prevalence of retinopathy among type 2 diabetic subjects was 15.2% The statistically significant associated factors were longer duration of diabetes, higher HbA1c, higher microalbumin, and female sex.

並列關鍵字

type 2 diabetes ； diabetic retinopathy ； prevalence ； associated factors