Jamu is the general name for traditional Javanese herbal elixirs, traditionally made by a Mbok Jamu (Jamu lady) or a dukun (traditional Javanese healer). This paper first examines why at this historical juncture the state has begun sponsoring a program to scientize Jamu within a cultural heritage context. Drawing on archival research and interviews given from 2017 to 2019, I posit that the urge to avoid recurrent scandals over fake Jamu, and the wave of nationalism which has been prevalent since 2007 have combined to create the conditions for the scientization of Jamu. This paper investigates how the government-sponsored RISTOJA (Riset Tumbuhan Obat dan Jamu [Research of Medicinal Plants and Jamu]) program acts as a database for Jamu scientization and remolds the cultural content of Jamu. In order to achieve the goal of scientizing, the program must face at least three integral aspects of Jamu: community-based bodies, geography-centered herbal knowledge, and authentic local healers.