高血壓患者頭髮化學元素的變化

Changes of Hair Chemical Elements in Patients with Hypertension

何邦平(Bang-Ping He) ； 趙德山(De-Shan Zhao) ； 李東方(Dong Fang Li) ； 王穎(Ying Wang) ； 王桂清(Gui-Qing Wang) ； 趙霖(Lin Zhao) ； 鮑善芬(Shan-Fen Bao) ； 王敏(Min Wang) ； 鄧京豐(Jing-Feng Deng)

《慈濟醫學雜誌》 5卷2期 (1993/06) Pp. 93-98

https://doi.org/10.6440/TZUCMJ.199306.0093

摘要

中風是中老年人死亡、致殘的主要原因，而高血壓是中風的最主要危險因素。為了探討微量元素含量變化與高血壓的關係，作者於1990年9月至1992年5月對我國中風高發區、低發區的15個省、市、自治區的25個研究監測點的62.5萬人進行人群調查，採用原子吸收分光光度計，檢測中風高危人群738例，頭髮微量元素Zn、Cu、Fe、Mn和常量元素K、Na、Ca、Mg，結果發現高血壓組的頭髮Na、Zn、Fe、Na/K和Zn/Cu明顯高於臨界高血壓和對照組，而K、Ca、Cu、Ca/Mg則比對照組低。K、Ca、Ca/Mg與收縮壓和舒張壓均呈顯著負相關，而Na、Zn、Fe、Na/K和Zn/Cu呈顯著正相關。K、Ca和Na與血壓關係最密切。

關鍵字

微量元素 ； 常量元素 ； 腦中風 ； 血壓

並列摘要

Stroke is a major cause of both death and disability in middle-aged and elderly people. Hypertension (HP) is the most important known risk factor for stroke. About 625 thousand people were involved from 25 research areas of 15 provinces, municipal cities and autonomous regions of the high and low stroke incidence in China during 1990.9 – 1992.5 to study the effect of trace elements on HP. The trace elements Zn, Cu, Fe, Mn, and ordinary elements Ca, Mg, K, Na in hair of 738 stroke-prone patients were determined with GGX-II Atomic Absorption Spectrophotometer. It was found that the contents of Na, Zn, Fe, and Na/K, Zn/Cu in HP were significantly higher than those in critical hypertension (CHP) and control, while K, Ca, Cu and Ca/Mg were significantly lower than those in CHP and control. There was a significantly negative correlation between K, Ca, Ca/Mg and blood pressure (BP), while a significantly positive correlation between Na, Zn, Fe, Na/k, Zn/Cu and BP. BP is closely related with K, Ca and Na.

並列關鍵字

trace elements ； ordinary elements ； stroke ； blood pressure