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糙薏仁對致敏鼠過敏反應之影響
Effect of Dehulled Adlay on Allergic Responses of Sensitized Mice
Abstracts
To investigate the effect of dietary dehulled adlay on allergic responses of sensitized animals, BALB/c mice aged six weeks were fed three different diets containing 0% (control group), 20% and 90% dehulled adlay, respectively. After six weeks’ feeding period, the mice were sensitized twice by intraperitoneal injection of ovalbumin and aluminum hydroxide, and then sacrificed two weeks later. During the feeding period, the apparent change of the mice, the body weight change and total feed intake were recorded. The mice were bled retroorbitally for serum ovalbumin-specific IgE and IgG(subscript 2a) antibodies determination. The results showed that there were no significant differences in the body weight, total feed intake and the relative tissue weight (except lung) of the mice (P＞0.05) among the three groups. Significantly lower serum anti-OVA IgE level and higher IgG(subscript 2a) level (P＜0.05) were noted in the 20% adlay group compared to those of the control group. Significantly higher serum anti-OVA IgE level was noted in the 90% adlay group compared to those of the control group. However, there was no significant difference in the serum anti-OVA IgG(subscript 2a) between the 90% adlay group and control group. In addition, the apparent change of mice was noted in the 90% adlay group. The hair became more yellowish, less lustrous and smoothless. The significantly lower serum anti-OVA IgE and higher IgG(subscript 2a) antibody productions in the OVA-sensitized mice fed 20% adlay diet suggesting that 20% adlay group might improve allergic effect, but not the 90% adlay diet.
Parallel abstracts
To investigate the effect of dietary dehulled adlay on allergic responses of sensitized animals, BALB/c mice aged six weeks were fed three different diets containing 0% (control group), 20% and 90% dehulled adlay, respectively. After six weeks’ feeding period, the mice were sensitized twice by intraperitoneal injection of ovalbumin and aluminum hydroxide, and then sacrificed two weeks later. During the feeding period, the apparent change of the mice, the body weight change and total feed intake were recorded. The mice were bled retroorbitally for serum ovalbumin-specific IgE and IgG(subscript 2a) antibodies determination. The results showed that there were no significant differences in the body weight, total feed intake and the relative tissue weight (except lung) of the mice (P＞0.05) among the three groups. Significantly lower serum anti-OVA IgE level and higher IgG(subscript 2a) level (P＜0.05) were noted in the 20% adlay group compared to those of the control group. Significantly higher serum anti-OVA IgE level was noted in the 90% adlay group compared to those of the control group. However, there was no significant difference in the serum anti-OVA IgG(subscript 2a) between the 90% adlay group and control group. In addition, the apparent change of mice was noted in the 90% adlay group. The hair became more yellowish, less lustrous and smoothless. The significantly lower serum anti-OVA IgE and higher IgG(subscript 2a) antibody productions in the OVA-sensitized mice fed 20% adlay diet suggesting that 20% adlay group might improve allergic effect, but not the 90% adlay diet.