纖維素是地球上蘊藏量最豐富的再生性碳水化合物,它們可被纖維素分解酵素水解成為葡萄糖,而提供作為生產生質能源之用。纖維素分解酵素在工業上有很大的應用價值,諸如燃料、紡織、動物飼料以及食品方面的加工利用。因為超過一半的工業酵素反應需要在高溫環境下進行,因此來自於細菌的熱穩定性纖維素分解在工業應用上具有潛在的利用價值。在細菌中,好氧和厭氧菌對於分解纖維素的策略有所不同,來自於熱穩定性纖維素分解菌的纖維素分解酵素能以可溶性或細胞聚集之形式產生。根據細胞特性探討和親緣關係的研究,包括16S rDNA序列以及纖維素分解酵素之胺基酸序列的比對分析,這些屬於醣甘水解酵素大家族中的熱穩定纖維素分解酵素可分成四個亞族。
Cellulose is the most abundant renewable carbohydrate on earth. Cellulases can hydrolyze cellulose into glucose thus it has the potential to be used for the production of biomass and biofuel. Cellulases have a wide range of industrial applications in the manufacture of fuel, textile, animal feed, and food. Because of more than half of the industrial enzymatic reactions were operated under high temperature, thermostable cellulases from bacteria are potentially valuable for industrial applications. Among the bacteria, there is a difference in cellulolytic strategy between the aerobic and anaerobic strains. Cellulases from thermostable cellulolytic bacteria must be produced that are either soluble or cell associated forms. Based on cellular characterizations and phylogenetic studies, including of 16S rDNA sequence and comparative cellulose amino acid sequences analysis, these cellulases belonging to the large family of glycoside hydrolases can be divided into four subfamilies.