可供快速鑑定微生物的新型感測科技

Novel Sensing Technologies for Rapid Identification of Microorganisms

潘永歷(Yong-Li Pan) ； 林其昌(Chi-Chang Lin) ； 張長泉(Tsung Chain Chang) ； 張憲彰(Hsien-Chang Chang)

《科儀新知》 156期 (2007/02) Pp. 4-15

https://doi.org/10.29662/IT.200702.0001

摘要

當人類及動植物不經意地遭受致病微生物的感染時，個人健康與公共衛生所受到的危害常是駭人聽聞的。為了預防這些災害問題發生，深入了解各種致病性微生物的特性，並積極發展新型感測科技以建立快速鑑定的方法是刻不容緩的。由於致病微生物涵蓋的種類極為多樣，本文將聚焦於細菌與黴菌，並透過系統性的方式介紹生物感測器、分子生物技術、免疫血清方法、介電泳晶片以及光譜儀器等五大類感測科技，更針對其重要檢測原理、微生物鑑定應用、技術發展現況與未來趨勢展望進行詳盡而深入的剖析。

並列摘要

When human beings, animals and plants are incidentally infected by pathogenic microorganisms, their endangerments to individual and public health are often shocking. In order to prevent and avoid these disasters, it is a great urgency to understand the characteristics of these microorganisms in depth and to develop novel sensing technologies zealously for creating rapid detection and identification methods. Because pathogenic microorganisms include various species, this article will focus on the introduction of bacteria and fungi. Then, we will systematically introduce five major sensing technologies, which are biosensors, molecular biological techniques, immunoserologic methods, dielectrophoretic chips and spectroscopy instruments. Furthermore, we will explicitly dissect their important detection principles, applications of microorganisms identification, current state of the art, future trends and prospectives.