增殖性視網膜病變一般認為是由於視網膜缺血釋出血管新生因子所致,本文報告一42歲男性,因右眼視力模糊及左眼脹痛前來求診,右眼視力為4/20,左眼無光覺,經檢查發現有雙眼增殖性視網膜病變及左眼新生血管性青光眼。經雷射與冷凍治療後,新生血管消退且眼壓獲得控制,但視力未見改善,回顧其病史,發現有高血壓合併腎功能不全,而沒有糖尿病與其它疾病。相關血液和X光檢查沒有異常,但是頸動脈超音波則發現有動脈硬化斑及管壁增厚的情形。由此例可知任何非糖尿病所致之增殖性視網膜病變均應予以全身性檢查與評估。
Proliferative retinopathy is thought to result from ischemic retina which releases angiogenic factors. We present a case of 42-year-old man who suffered from progressive blurred vision in the right eye and pain in the left eye. The visual acuity were 4/20 (OD) and negative light sense (OS). Ocular examination revealed proliferative retinopathy (OU) and neovascular glaucoma (OS). After panretinal photocoagulation (OD) and cryoretinopexy (OS), the neovasculization were alleviated and intraocular pressure was under control, but visual acuity were stationary. He had hypertension with renal insufficiency, but no DM or other systemic diseases were found. Related laboratory and radiologic studies were not contributory. Carotid duplex ultrasonography showed atherosclerotic plaques and diffuse arterial wall thickening. Any nondiabetic proliferative retinopathy should be evaluated systemically.