Thermal/fluid analysis for electronics cooling designs has become an integral part in the research, development and manufacturing of new electronic components. Methods to resolve the geometric complexity and length/time scale differences in fluid dynamics and thermodynamics have been developed and validated in order for the general acceptance of the design analysis tools. General approaches using parched grid method to bridge the domains for the fluid flow and the heat generating/conducting solid components are described in this paper. A computational fluid dynamics (CFD) method for the solutions of the Navier-Stokes equations with conjugate heat transfer model is outlined. Some benchmark and illustrative numerical test cases are presented. Issues concerning the development of a robust and reliable design tools for electronics cooling are also discussed.