- 期刊
Laryngeal Small Cell Carcinoma-A Case Presentation and Review of the Literature
咽喉小細胞癌：個案報告與文獻探討
摘要
肺外小細胞癌症是一個相當罕見的疾病，身體任何地方都可能產生。根據文獻報告記載，其最常出現於腸胃道、生殖泌尿道以及頭頸部。頭頸部小細胞癌中以咽喉小細胞癌最為常見，但其預後相當差，兩年以及五年的存活率分別約為16%以及5%。預後較差的主要原因是因其常有頸部淋巴結侵犯以及早期遠處轉移。目前，單以手術治療咽喉小細胞癌是不夠的，首選治療應以白金為基礎的化學治療輔以或不輔以放射線治療。即便如此，咽喉小細胞癌的預後仍相當差，所以在考慮治療方式時應該以患者的生活品質為優先考量。在此我們提出一位經緊急氣切手術後才診斷的咽喉小細胞癌案例，其臨床則是以六個月內漸進式呼吸困難、喘鳴以及血氧低下來表現。
並列摘要
Extrapulmonary small cell carcinoma is a rare disease entity that can be found anywhere in the body, especially in the gastrointestinal tract, genitourinary tract, and head and neck areas. Laryngeal small cell carcinoma has a poor prognosis with 2- and 5-year survival rates of only 16% and 5%, respectively. It often presents with local invasiveness to cervical lymph nodes and early distant metastasis. Surgery alone is not enough for tumor eradication, and platinum-based chemotherapy with or without radiotherapy should be considered first. The patient's quality of life should be emphasized because of the poor prognosis. Herein, we report a case of laryngeal small cell carcinoma diagnosed after emergent tracheostomy with the initial presentation of progressive dyspnea followed by desaturation and stridor for 6 months.
延伸閱讀
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