Schwannoma of Transverse Colon Mimicking Carcinoma: A Case Report

模仿癌症的橫結腸神經鞘瘤

沈明宏(Ming-Hung Shen) ； 張世昌(Shih-Chang Chang) ； 黃其晟(Chi-Cheng Huang) ； 李興中(Henry Hsin-Chung Lee) ； 陳樞鴻(Shu-Hung Chen)

《中華民國大腸直腸外科醫學會雜誌》 27卷4期 (2016/12) Pp. 187-190

https://doi.org/10.6312/SCRSTW.2016.27(4).10508

摘要

神經鞘瘤是一種少見的胃腸道間質腫瘤。這篇文章描述一個看起來像癌症的橫結腸神經鞘瘤，症狀主要是以血便來表現。這位64歲的女性，已經持續有兩個月的血便。大腸鏡發現橫結腸有一個腫瘤，病理切片呈現為急慢性發炎。在經過根治性右半結腸切除術後，術後病理報告為梭形細胞腫瘤。免疫組織染色呈現S-100為強烈廣泛性陽性，而對於CD117、CD34及smooth muscleactin為陰性。根據免疫組織染色結果，最後的病理診斷為橫結腸神經鞘瘤。

關鍵字

神經鞘瘤 ； S-100

並列摘要

Schwannomas are rare gastrointestinal mesenchymal tumors. We report a schwannoma of the transverse colon mimicking a carcinoma with presentation as hematochezia. A 64-year-old woman had been passing bloody stool since 2 months. The colonoscopy showed a solitary and elevated polypoid tumor in the transverse colon, and biopsies revealed acute and moderate chronic inflammation. The patient underwent radical right hemicolectomy, and the histology finding was a spindle cell tumor. The immunohistochemical results revealed strong and diffuse positivity for S-100, and negativity for CD117, CD34, and smooth muscle actin. Therefore, the final pathological diagnosis was a schwannoma.

並列關鍵字

Schwannoma ； S100

參考文獻

1. Prevot S, Bienvenu L, Vaillant JC, de Saint-Maur PP. Benign schwannoma of the digestive tract: a clinicopathologic and immunohistochemical study of five cases, including a case of esophageal tumor. Am J Surg Pathol 1999; 23: 431-6.

3. Seno K, Itoh M, Endoh K, Joh T, Yokoyama Y, Takeuchi T, et al. Schwannoma of the duodenum causing melena. Intern Med 1994; 33: 621-3.

5. Ito S, Matsumoto H, Kogure H, Kaneko Y. A case of transverse colon schwannoma. J Jpn Soc Colo-proctol 1996;49:139-43.

6. Mysorekar, V.V., Rao, S.G., Jalihal, U. and Sridhar, M. Schwannoma of the Ascending Colon. Indian Journal of Pathology and Microbiology. 2010; 53: 198-200.

7. Tomozawa S, Masaki T, Matsuda K, Yokoyama T, Ishida T, Muto T. A schwannoma of the cecum: case report and review of Japanese schwannomas in the large intestine. J Gastroenterol 1998; 33: 872-5.