This article describes an caring experience for a woman of her first pregnancy who was hospitalized due to early uterus contraction. Between December 10th 2009 and January 4th 2010, the author used skills of observation, interview, physical assessment to collect data in physical, psychological, social and spiritual domains. Three major health problems were found: anxiety, changes of comfort status, and health seeking behaviors. The client's knowledge and ability of self-care was improved by means of monitoring and maintaining safety of clients and her baby, meeting her basic physical needs and comfort, and providing information of tocolysis. In addition, the author also provided nursing interventions such as mental support to eliminate anxiety, family support and experience sharing to help the client, baby and family achieve adaption, and help them go through the crisis of premature labor.