The theory of "Integrative Medicine" and "Medicine-Yi Interaction" in the book entitled "Medicine and Yi in General Science" by Late Qing physician TANG Ching-Hai, is well known now. This article aims to establish the system of analysis and application from TANG's Yin-Yang medical thoughts, and let us to know the Yin-Yang in Yi-Ching. So that we can know more about medicine-yi interaction in integrative medicine.