With the development of science and technology, online teaching has become increasingly prominent in the field of education. As a new mode of education and teaching, educational administrators, teachers and students will accept the challenge and constantly adapt. Fundamentals of Nursing is a professional basic and core course for nursing students. In addition to basic theories and knowledge, it also includes a large number of basic technical operations, so it puts forward higher requirements for the design and implementation of online teaching. This paper elaborates on the operation mode of online teaching, carefully analyzes the advantages and disadvantages of online teaching based on the online learning traces of students and the results of the questionnaire survey, and puts forward corresponding countermeasures for various problems.