This paper explains the basic concepts of innovation and entrepreneurship education and professional education, and analyzes the differences and relations between innovation and entrepreneurship education and professional education. After investigating the current situation of the integration of innovation and entrepreneurship education and professional education, this paper explores the way of the integration of innovation and entrepreneurship education and professional education based on electronic information major. This will help to improve the quality of innovation and entrepreneurship education and professional education, so as to improve the training quality of innovation and entrepreneurship talents.