This paper analyzes the main problems existing in the teaching content design, teaching mode, practical links and the infiltration between related courses of international logistics course, and puts forward some suggestions for the teaching reform and innovation of international logistics course in order to cultivate applied logistics talents. International logistics is the basic course of logistics engineering specialty and the core of cultivating logistics management talents. For a long time, the teaching of international logistics in undergraduate colleges has paid too much attention to theoretical knowledge and ignored the cultivation of practical skills, which makes it difficult for the trained talents to meet the job requirements. Practical teaching is the key to cultivating excellent talents. Conventional practical teaching highlights the construction of practical training base in the school and lacks the combination with practical projects. Building a practical teaching model guided by the project library, innovating practical teaching methods, integrating industry standards and increasing practical teaching hours, and building corresponding teaching models for students can effectively improve the teaching quality of international logistics.